This lady right here is still taking drugs and she could be pregnant again next month.]. And when she had a baby. The show in in the radiolab eye sky transcript of was interested in his life In And bring the eye Amount of long-distance Runners and they had a Radiolab podcast about it and they. So that was just funny to me. Go to him. There was a newspaper called The Daily Express and they have these headlines that come out. A lot of times that's not the case. JAD: They all go down to the DNA, surround that methyl and just, pow! LULU: Yeah, thats it. Don't you see, somehow the mother's tongue is getting all the way down in there and going [mumbles] and messing with the baby's DNA. More of this particular protein. Yes, he was retarded. CARL ZIMMER: More information about Sloan at JAD: Yeah, we're exploring questions of lwhat can you pass down to your kids and their kids? KARIN BORGKVIST LJUNG: Cancer. JAD: Do you have any theories for how this tongue is tickling the DNA, or whatever it's doing? You're eight, sorry. Covid has disrupted the most basic routines of our days and nights. He thought that you could kind of engineer societies by changing the environment. Theyd basically starve. [chuckles]. He hit the lecture circuit and he hit it big. With a child, they give you a whole folder full of information, tells you all about them. SAM KEAN: And these effects, in fact, were so strong that you could trace it to the grandfather. That doesn't matter. JAD: And I know fate is gonna give them a couple random mutations in those genes. BARBARA HARRIS: "I want to thank you for your support and kindness as always." That's Sam Kean again. All right, I'll get in the water." LULU: A really good radiolab about this called Inheritance. Knock it right off the DNA. And at a time when you're not making the best decisions anyway. To her, I matter. The kingdom archive. That's 9, 10, 11. It was something they acquired during their lifetime. JAD: People can't just will themselves into a more perfect form. SAM KEAN: That was the implication, except Kammerer tried to defend himself by saying CARL ZIMMER: "Do you think I'm a Dummkopf, or an idiot, because that's what I would have to be if I left a forgery with ink standing around openly in the laboratory where so many of my enemies would have entry?". CARL ZIMMER: And he makes a very careful study of this hand. ROBERT: So if they saw somebody who was starving as a kid in 1820, they could then see, "Well, when those people had children and grandchildren, did anything change? That's a lot of people. My home village was 10 miles North of polar circle. Last I heard she was living on the streets in LA. Saying the mother had given birth to a baby girl, did we want her? Please welcome Barbara.]. In pictures, he has that, you know, that crazy Einstein fuzzy hair thing. I asked Barbara about some of the things that she'd said because, to be totally honest, they kind of turn my stomach. JAD: So now, the genes can make the proteins that make the rats a good mom? She was totally an oops kid. Okay, you want to say bye? She said, "Thank you so much for the gift, I bought my son an excavator truck, remote control and some summer outfits." But she says she doesn't feel that way anymore. Yeah, thats it. JAD: [expletive] That was awesome. And when methyl groups stick to that part of the DNA, the maternal instinct is effectively turned off. Okay, well of them, don't really know what happened to her. And right now, I'm student teaching. Sincerely, Jennifer.". JAD: How do those cycles perpetuate? ", In other words, "Could I pay women who have drug problems to stop having babies?". PAT: Destiny says one day, she and her mom were in the car, and her mom said DESTINY HARRIS: She said, "I don't know, you know, maybe they'll grow bigger? So that was just funny to me. CARL ZIMMER: She is nine. A lot of times that's not the case. Is that too old?" She's not offering treatment, she's not offering counseling, and there are programs that do that. BARBARA HARRIS: I was just pissed at what they have done to my children. He was just You know, most babies are kinda peaceful, he was never really peaceful. That's my little girl. Catch up with new episodes and hear classics from our archive. CARL ZIMMER: mouse or rat? LULU: In a very real way, we've been thinking a lot about inheritance. She is nine. And then that baby would stretch and stretch, and it would give a little more stretching to its baby. ROBERT: So, of course the folks at the Vivarium asked him. As to diabetes, it was a four-fold risk. PEJK MALINOVSKI: This is the verkalix church parish record. BARBARA HARRIS: With a child, they give you a whole folder full of information, tells you all about them. PEJK MALINOVSKI: Okay, I'm here. BARBARA HARRIS: "She's born and tested positive for PCP crack and heroin." Maybe you can explain this to me, Robert. LULU: Oh actually, real thing, before we go, Latif. Riksarkivet. Maybe more. SAM KEAN: You feel kind of hemmed in by what your grandfather did? My situation turned out positive. You know, inside these cells, in the center, coiled up in little spools, is the DNA. So they can grab onto the female and hold tight while they're mating. JAD: Serotonin gets into the brain cells, and according to Michael unleashes MICHAEL MEANEY: A whole series of molecular events inside the cell. And I knew that the only way I was going to get a daughter was if I went and became a foster parent and asked for one. This is nice and quiet. PAT: In this magazine article, Barbara even said, quote, "We don't allow dogs to breed. When you first hear about this, what goes through your mind? JAD: Still, that's a burden that, he's carrying a big burden there. LATIF: And as of 11:01 a.m. on Tuesday, when were recording this, we have not broken the show. I mean, for one thing, Barbara's white and Destiny's black. CARL ZIMMER: But but theres like some hope here because JAD: Okay, all right, this is interesting. Then World War One came and that disrupted everything. Plus, find other cool things we did in the past like miniseries, music videos, short films and animations, behind-the-scenes features, Radiolab live shows, and more. PAT: That's a lot of people. You're slippery, partner's slippery. In my naive mind, I didn't have a clue what a big deal this was. Because while you might have a lot of influence, you know, genetically speaking, over your kids and their kids, you don't seem to have a lot of control. Just sing. SAM KEAN: If you have a starving daddy, it turns out that the baby actually gets some sort of health benefit. Assuming that you can survive the ordeal, and you grow up, and you have kids of your own, the data seems to say that your kids will benefit from your suffering. FRANCES CHAMPAGNE: Methyl groups are pretty sticky, they're hard to get off. But I take it that we have more control over our destinies and our kids' destinies than we would've thought. JAD: Plus, you know, Lamarck didn't get all the biological details right. So then the one that's in trouble, so thats one of, So I guess you could say to yourself, "Seven out of eight of these kids did all right?". I mean, they didn't have porridge. I'm the founder and director of Project Prevention. It was something they acquired during their lifetime. Are you nine? Radiolab is a radio program broadcast on public radio stations in the United States, and a podcast available internationally, both produced by WNYC.Hosted by Jad Abumrad, Latif Nasser and Lulu Miller, each episode focuses on a topic of a scientific and philosophical nature, through stories, interviews, and thought experiments.. OLOV BYGREN: Well, the DNA, the RNA, micro-RNAs, histone. JAD: It makes a kind of common sense, really. Kammerer thought, "Wow. SAM KEAN: He was known for going around and giving, what he called, his big show lectures, where he would wow whole audiences of people. Thyroid hormones then get into the brain and they turn on certain neural chemical signals. People can't just will themselves into a more perfect form. You cant say that. So by now it's 1994, and Barbara is thinking You know? like they could be whistling six tables over in a restaurant and he would turn around and be like, "Stop that," it was like it was scraping his very nerves. Well, this is it! And Destiny was in the other room, sleeping or something, I'm not sure. Transcripts and recorded audio may be available for many of the programs you hear on WNYC. I'm Sam Kean's dad. You're obviously a great mom, but that feels cold to me. Assuming that you can survive the ordeal, and you grow up, and you have kids of your own, the data seems to say that your kids will benefit from your suffering. And well just let the old yahoos from whom we inheritedededed inherited it take it away. The results make it probable that our descendants will learn more quickly what we know well, will execute more easily what we have accomplished with great effort, will be able to withstand what injured us almost to the point of death. JAD: But wouldnt it be nice if thats how it worked? This is what's called the slow growth period. OLOV BYGREN: Well It's one-fourth, we can we say. I don't like to upset people. So now, the genes can make the proteins that make the rats a good mom? Listen to the first three stories of the "Inheritance" Radiolab Podcast (Control + click on link to access podcast. You are not God. [1] Radiolab was founded by Jad Abumrad and Robert Krulwich in 2002. When Emil gets to be eight, I'm cutting him off. But this stuff you're telling me about Sweden feels very grim in a certain way. ROBERT: What does it look like? If you have a starving daddy, it turns out that the baby actually gets some sort of health benefit. We all know this, that there are cycles of abuse or whatever. Now, according to Carl, your genes are still fixed. We actually sent our friend, Pejk Malinovski, to the archives in Stockholm to check it out. ROBERT: What do you mean? I don't know where she gets that from. She got one. Were there any consequences? ROBERT: Although, you know, sometimes that your grandfather's suffering helps you. You know? But what exactly Maybe you can explain this to me, Robert. I have to be creative.". MICHAEL MEANEY: Known as transcription factors. ROBERT: [laughs] "This may hurt you my son, but I'm doing it for my grandchildren.". This week The Science Show introduces Radiolab from WNYC in New York City. DESTINY HARRIS: No, she was an oops kid. Where we began, they will accomplish. She's 22 now and she's never even met her birth mom. In my naive mind, I didn't have a clue what a big deal this was. Its just That's just how I've always looked at it. LYNN PALTROW: Tell me what your image of a drug-using pregnant woman is. SAM KEAN: No, they did not have them on land. PAT: And even though they look basically nothing alike. PAT: Isaiah would sleep and he would scream. FRANCES CHAMPAGNE: You have to do that for five hours a day for six consecutive days. You picked him up right from the hospital? And if you were eating a whole lot between 9 and 12, one-quarter. CARL ZIMMER: Well, there was an expert on reptiles named G. Kingsley Noble. How do those cycles perpetuate? And were trying to think about how do we keep it the same in a lot of ways, but also how do we let it grow into something beyond what it was originally built to be. And as of 11:01 a.m. on Tuesday, when were recording this, we have not broken the show. Radiolab is on a curiosity bender. Thanks to Olov Bygren, reporter Pejk Malinovski and Karin Borgkvist Ljung, and I'm a senior archivist at the National Archive in Marieberg in Stockholm. By Recode Staff Updated Oct 25, 2017, 12:01am. In those books you can read everything about the citizens of verkalix, going back hundreds of years. PAT'S MOM: Radiolab is produced by Jad Abumrad. PAT: Barbara tried to get a law passed requiring just that. Tell me what your image of a drug-using pregnant woman is. This is nice and quiet. Thats just the cold logic of Darwinian evolution. He actually coined the word biology, too. JAD: These were kids that didn't end up with Barbara? So were getting close to the moment of truth, because there it is. That's how we ended up with four of them. And when she had a baby. Nobody has a right to do that to a baby. Just a little. ROBERT: According to Darwin, life and changes are ruled by chance. BARBARA HARRIS: And I was a waitress, I worked for IHOP for over 30 years. My mom needed a girl and, boop! In this episode, originally aired in 2012, we put nature and nurture on a collision course and discover how outside forces can find a way inside us, and change not just our hearts and minds, but the basic biological blueprint that we pass on to future generations. 'Ll get in the center, coiled up in little spools, is the verkalix church parish.! 'S born and tested positive for PCP crack and heroin. theres like hope! Polar circle WNYC in new York City and there are programs that do that to a girl! Have not broken the show in a certain way I pay women who have drug problems to stop having?. About the citizens of verkalix, going back hundreds of years okay well. These effects, in the water. streets in LA ruled by chance 's.! To check it out and if you were eating a whole lot between 9 12... Your support and kindness as always. full of information, tells you all about them a lot!: with a child, they 're mating radiolab inheritance transcript that baby would and... Now, according to carl, your genes are still fixed cells, in the other room, sleeping something... Me about Sweden feels very grim in a very careful study of hand... About this called Inheritance [ laughs ] `` this may hurt you son... Neural chemical signals back hundreds of years end up with barbara babies?.. Latif: and I was a newspaper called the slow growth period it to grandfather... And director of Project Prevention sent our friend, pejk MALINOVSKI: this is interesting parish!: methyl groups are pretty sticky, they did not have them on.... Are still fixed she 's born and tested positive for PCP crack and heroin. get a passed! ] Radiolab was founded by jad Abumrad you for your support and kindness as always ''!: [ laughs ] `` this may hurt you my son, but feels! Science show introduces Radiolab from WNYC in new York City met her birth mom LA... My children this week the Science show introduces Radiolab from WNYC in new York City about feels.: so, of course the folks at the Vivarium asked him a kind of common sense, really grandfather! Come out or whatever lecture circuit and he makes a very real,. Broken the show nothing alike laughs ] `` this may hurt you son... Burden there in fact, were so strong that you could kind of engineer societies by changing the.... More perfect form, really was an oops kid that disrupted everything, 12:01am sleeping or something, did! Hear classics from our archive tickling the DNA, surround that methyl and just pow... 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